Causes of autism research paper

Thalidomide: According to the . Food and Drug Administration (FDA), thalidomide is a drug that was marketed outside of the United States in the late 1950’s and early 1960’s. It was used as a sleeping pill, and to treat morning sickness during pregnancy. However, its use by pregnant women resulted in the birth of thousands of babies with severe malformations. Thalomid (thalidomide) is approved in the . to treat the painful, disfiguring skin sores associated with leprosy, and to prevent and control the return of these skin sores. Distribution of and access to thalidomide is strictly controlled to prevent its use during pregnancy. A pregnant woman or any woman thinking about becoming pregnant must not take Thalomid (thalidomide), because it is known to cause severe birth defects or death to an unborn baby, even after taking just one dose. When a woman of child-bearing age has no other appropriate treatment choice and must take Thalomid (thalidomide), there are many precautions that must be taken to avoid pregnancy. To view these steps and to find out additional information, go to http:///cder/news/thalinfo/.

Research Autism  is an independent, non-profit making charitable trust committed to improving the lives of autistic people through research into new and existing health, education, social and other interventions. 

Research Autism has achieved certification to the Information Standard , and its website is an authoritative source of comprehensive, impartial information about  autism interventions . They look at what interventions claim to do and whether or not there is any evidence to back up the claims.

Autism, in short, seems to be the end result or "final common pathway" of numerous disorders that affect brain development. Also, brain studies have demonstrated that persons with autism tend to have a number of abnormalities in brain size. In general, however, when clinicians make the diagnosis of autism, they are excluding the known causes of autistic behaviors. However, as the knowledge of conditions that cause autism advances, fewer and fewer cases will likely be thought of as being "pure" autism and more individuals will be identified as having autism due to specific causes.

Several lines of evidence point to synaptic dysfunction as a cause of autism. [11] Some rare mutations may lead to autism by disrupting some synaptic pathways, such as those involved with cell adhesion . [62] Gene replacement studies in mice suggest that autistic symptoms are closely related to later developmental steps that depend on activity in synapses and on activity-dependent changes. [63] All known teratogens (agents that cause birth defects ) related to the risk of autism appear to act during the first eight weeks from conception , and though this does not exclude the possibility that autism can be initiated or affected later, there is strong evidence that autism arises very early in development. [64]

Causes of autism research paper

causes of autism research paper

Several lines of evidence point to synaptic dysfunction as a cause of autism. [11] Some rare mutations may lead to autism by disrupting some synaptic pathways, such as those involved with cell adhesion . [62] Gene replacement studies in mice suggest that autistic symptoms are closely related to later developmental steps that depend on activity in synapses and on activity-dependent changes. [63] All known teratogens (agents that cause birth defects ) related to the risk of autism appear to act during the first eight weeks from conception , and though this does not exclude the possibility that autism can be initiated or affected later, there is strong evidence that autism arises very early in development. [64]

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